Hypocalcemia in pancreatitis is associated with

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Multiple Choice

Hypocalcemia in pancreatitis is associated with

Explanation:
In pancreatitis, low calcium levels reflect more extensive fat necrosis and a stronger systemic inflammatory response. Pancreatic lipase releases fatty acids that bind calcium to form insoluble calcium soaps, pulling calcium out of the circulation. The amount of calcium sequestration increases with disease severity, and severe pancreatitis with organ dysfunction tends to have higher mortality. Therefore hypocalcemia is a marker of worse prognosis and is associated with increased mortality. The other options would imply better or unchanged outcomes, which does not fit the link between calcium depletion and severe disease.

In pancreatitis, low calcium levels reflect more extensive fat necrosis and a stronger systemic inflammatory response. Pancreatic lipase releases fatty acids that bind calcium to form insoluble calcium soaps, pulling calcium out of the circulation. The amount of calcium sequestration increases with disease severity, and severe pancreatitis with organ dysfunction tends to have higher mortality. Therefore hypocalcemia is a marker of worse prognosis and is associated with increased mortality. The other options would imply better or unchanged outcomes, which does not fit the link between calcium depletion and severe disease.

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